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The
First Part：Basic
Knowledge of Metastatic Prostate Cancer
What Is
Metastatic Prostate Cancer
If your
prostate cancer spreads to other parts of your body, that it's "metastatic" or
that your cancer has "metastasized."
There are
two types of metastatic prostate cancer:
1) Local
metastasis: Prostate cancer with local metastasis means that the cancer has
spread to other organs within the pelvis. This usually means the local lymph
nodes, but can include any organ or structure in the pelvis.
2) Distant metastasis: Distant metastasis means that the prostate cancer has
spread beyond the pelvis. The bones, spine, brain, liver, and lungs are common
sites of cancer metastasis.
It's
still prostate cancer, even when it spreads. For example, metastatic prostate
cancer in a bone in your hip is not bone cancer. It has the same prostate cancer
cells the original tumor had.
Metastatic prostate cancer is an advanced form of cancer. There's no cure, but
you can treat it and control it. Most men with advanced prostate cancer live a
normal life for many years.
The goals
of treatment are to:
1) Manage
symptoms.
2) Slow
the rate your cancer grows.
3) Shrink
the tumor.
How
Prostate Cancer Spreads
Cancer
cells sometimes break away from the original tumor and go to a blood or lymph
vessel. Once there, they move through your body. The cells stop in capillaries
-- tiny blood vessels -- at some distant location.
The cells
then break through the wall of the blood vessel and attach to whatever tissue
they find. They multiply and grow new blood vessels to bring nutrients to the
new tumor. Prostate cancer prefers to grow in specific areas, such as lymph
nodes or in the ribs, pelvic bones, and spine.
Most
break-away cancer cells form new tumors. Many others don't survive in the
bloodstream. Some die at the site of the new tissue. Others may lie inactive for
years or never become active.
Why the
prostate cancer is prone to bone metastasis?
The
symptoms of prostate cancer at the early stage are not too obvious, with about
30% of patients having had the cancer spread at the time of their diagnosis, and
70% of them having had bone metastases, which usually occurs in multiple parts,
with only 10% of the metastatic patients in a single part.
Bone
metastasis occurs mostly in the middle axle bone, such as the vertebrae and
pelvis, accounting for about 80% of bone metastasis, followed by ribs, femur,
and humerus.
The
Clinical data show that in our body, every gram of tumor tissues can release 3
to 4 million cancer cells into the blood per day, but most of them will be
cleared away by immune cells in the blood. On the one hand, the bone has very
rich blood circulation, and on the other hand, the arteries and veins of the
bone are widely matched; and the diameter of the vein network is also large with
fast blood supply, so the cancer cells easily enter the bone cavity. Most of
bone metastases occur in the red bone marrow of the central axis, where the
blood flow is abundant and slow, so cancer cells that are not cleared away by
immune cells tend to stay in these parts, forming metastases.
1) The
first symptom of bone metastasis of prostate cancer is most of patients will
have bone pain as long as bone metastasis occurs, and this pain will continue to
be dull and painful, so the daily life of the patients will be affected.
2) The
second symptom of bone metastasis of prostate cancer is cancer cells will
destroy the hematopoietic stem cells of red blood marrow, and patients will have
such symptoms as anemia, weight loss, low fever, fatigue, and loss of appetite,
etc.
3) The
third symptom of bone metastasis of prostate cancer is after the patient has
bone metastasis, the cancer cells will erode the bone little by little, and the
bone will become more and more fragile, prone to have pathological fracture.
Fracture has a significant relationship with the bone metastase lesion
accounting for the proportion/size of bone diameter. When the bone metastasis
lesions are more than 2/3 of the bone diameter, the incidence of fractures can
reach 81%. If the cancer cells get further transferred, they will be spread to
the spine, and the collapse of the centrum will cause the symptom of spinal cord
to be compressed, which makes treatment become very difficult.
How Doctors
Find Metastatic Prostate Cancer
When you
are diagnosed with prostate cancer, your doctor will order tests such as:
X-rays；CT
scans；MRI scans；PET scans.
These
tests may focus on your skeleton and in your belly and pelvic areas. That way
doctors can check for signs that the cancer has spread.
If you
have symptoms such as bone pain and broken bones for no reason, your doctor may
order a bone scan. It can show if you have metastatic cancer in your bones.
Your
doctor will also ask for blood tests, including a check of PSA levels, to look
for other signs that the cancer is spreading.
PSA is a
protein made by the prostate gland. A rise in PSA is one of the first signs your
cancer may be growing. But PSA levels can also be high without there being
cancer, such as if you have an enlarged prostate or a prostate infection.
On
average, 8 years pass from the time a man is first diagnosed with prostate
cancer to the discovery that it has become metastatic. If you've had prostate
cancer, work with your doctor to check your risk and set a schedule for routine
PSA checks.
Metastatic
Prostate Cancer Symptoms
Man
experiencing painful urination because of a prostate problem. Potential symptoms
of prostate cancer include difficulty urinating, pain during urination, and a
sense of needing to urinate urgently.
Symptoms
of prostate cancer can include:urinary urgency；difficulty
starting or stopping urination；weak or interrupted urine flow；painful or burning
urination；erectile dysfunction；painful ejaculation；blood in the urine or semen。
Anyone
experiencing these symptoms should consult with their doctor as soon as
possible. While many other conditions can cause similar symptoms, it is
important to rule out prostate cancer.
Once a
person has been diagnosed with prostate cancer, the signs of metastasis will
vary depending on the where the cancer spreads and how quickly it is growing.
For
example, a person with prostate cancer and local metastasis to nearby lymph
nodes may not experience any change in symptoms.
However,
a person with metastasis to the bones may experience bone pain.
Other
symptoms of metastasis may include:fatigue；feeling
unwell；reduced appetite；weight loss；swelling in the legs or feet。
Metastatic
Prostate Cancer Complications
Advanced
prostate cancer can cause many other health problems depending on where the
cancer has spread to and how quickly it is spreading.
1)
Urinary problems: Cancerous growths can press on the bladder, urethra, or other
pelvic organs. Prostate cancer can also spread to those organs and cause urinary
retention, blood in the urine, incontinence, and difficulties emptying the
bladder.
2) Bowel
problems: Advanced prostate cancer can cause bowel problems, such as
constipation, diarrhea, urgency, obstruction, and incontinence. This is often
due to the use of pain medications, or the spread of prostate cancer to the
bowel or rectum. Dietary changes, dehydration, and inactivity can also cause
bowel problems.
3) Sexual
problems: It is not uncommon for men with advanced prostate cancer to have
difficulties getting or maintaining an erection. Some men also have decreased
libido or an inability to ejaculate.
4) Bone
pain or fractures: Prostate cancer that has spread to the bones can cause
significant bone pain. It can also weaken the bones, making a person susceptible
to breaks and fractures.
5)
Hypercalcemia: Calcium is stored in the bones but can leak out into the blood if
prostate cancer spreads to the bones. High levels of calcium in the blood can
cause fatigue, increased thirst or need to urinate, nausea and vomiting,
constipation, and loss of appetite.
6)
Anemia: Anemia means a decrease in the number of red blood cells that are
available to carry oxygen throughout the body. This can lead to severe fatigue,
shortness of breath, and looking pale. It is usually caused by cancer that has
spread to the bone marrow but can also be a side effect of cancer treatments.
7)
Lymphedema: Prostate cancer that has spread to the lymph nodes can cause
blockages within the vessels that transport lymph around the body. This causes
swelling in the legs or scrotum.
Metastatic
Prostate Cancer Prognosis
The
prognosis for advanced prostate cancer depends on where the cancer has spread
and how aggressively it is growing.
According
to the American Cancer Society, survival rates are as follows:
1) Local
prostate cancer without spread has a 5-year survival rate at nearly 100 percent.
2) Prostate cancer with local
spread also has a 5-year survival rate at nearly 100 percent.
3) Prostate cancer with
distant metastasis has a 5-year survival rate of around 29 percent.
These are
general statistics; it is important for a person with prostate cancer to speak
to their doctor about their specific case.
The
Metastatic Prostate Cancer Traditional treatments
There are
many types of traditional treatments available for advanced prostate cancer. A
doctor or oncologist will develop a treatment plan that takes into account the
individual's symptoms, prognosis, goals for treatment, age, and general health.
1)
Hormone therapy
Hormone
therapy for advanced prostate cancer shuts down the production of male sex
hormones. This can help prevent the cancer from continuing to grow. Common drugs
include abiraterone (Zytiga) and enzalutamide (Xtandi).
2)
Chemotherapy
Chemotherapy is a type of medication that destroys cancer cells or prevents them
from multiplying. People are usually given chemotherapy once the prostate cancer
has stopped responding to hormone therapy.
Chemotherapy is usually a combination of two or more drugs that are administered
intravenously, injected, or taken as a pill.
3)
Immunotherapy
Immunotherapy is a type of medication that modifies the body's immune system to
find and destroy cancer cells.
4)
Treatment for prostate cancer that has spread to the bones includes drugs such
as zoledronic acid (Zometa) and denosumab (Xgeva).
Treatment
for local metastatic cancer may also include radiation therapy.
Side
effects of the prostate cancer traditional treatments
Prostate
cancer treatment can cause some serious side effects, including:infertility；urinary
incontinence；urinary retention；diarrhea；erectile dysfunction；pain；fatigue；hair
loss；loss of appetite；nausea and vomiting，etc。
A person
should not feel the need to "power through" or suffer from uncomfortable
symptoms. It is important for anyone undergoing treatment to communicate with
their healthcare team about any side effects they are experiencing.
The Second
Part：3D
Precision & Targeted Therapy on the Latest Theory of Treating Metastatic
Prostate Cancer
Metastatic Prostate Cancer is a systemic disease and its treatment is a systems
engineering, it needs the combination of multi-specialty and multi-discipline in
theory and practice. In addition, patients should have a full understanding of
their own diseases, abandon some traditional misconceptions, avoid the influence
of all adverse factors that have carcinogenic effects, including some
traditional treatments with many side effects, completely change unhealthy
lifestyles, and re-establish and develop healthy internal environment and all
positive factors that have anti-cancer effects.
3D
Precision & Targeted Therapy in the research and treatment of Metastatic
Prostate Cancer has combined with our latest research and the most advanced
evidence in the world, and we propose the following new theory of Metastatic
Prostate Cancer Treatment.
(I)
Proto-oncogene and tumor suppressor genes
Each
person has proto-oncogenes and a tumor suppressor genes in the body, and both
the proto-oncogene and the tumor suppressor gene are genes that play an
important role in cell growth, proliferation and regulation. A tumor is
essentially a genetic disease. Various environmental and genetic carcinogenic
factors cause normal cellular DNA damage, thereby activating oncogenes and/or
inactivated tumor suppressor genes, plus damage apoptosis-regulating genes, and
DNA repairing genes, which are the basis of malignant tumors.
The
proto-oncogene refers to an oncogene that is present in the genome of a
biological normal cell. Under normal circumstances, the proto-oncogene is in a
low or no expression state and plays an important physiological role. The
proteins encoded by proto-oncogene are mostly cell growth factors and growth
factor receptors important for normal cell growth, such as PGF, FGF, EGF, TK,
STAT, and CDK, etc.
The tumor
suppressor gene is a gene that inhibits cell growth in normal cells and has a
potential tumor suppressor effect. The tumor suppressor gene plays a very
important negative regulatory role in controlling cell growth, proliferation and
differentiation. The tumor suppressor gene and the proto-oncogene restrict each
other and maintain the relative stability of the positive and negative
regulatory signals.
However,
under the action of certain carcinogens, the proto-oncogene can be activated and
transformed into an oncogene, which induces the cells to become cancerous. Under
the action of carcinogen, when the inactivation of tumor suppressor gene occurs,
malignant transformation of cells can be caused, thus leading to the occurrence
of tumor.
There are
many types of proto-oncogenes and tumor suppressor genes. The proto-oncogene
family includes the ras gene family, the myc gene family, the src gene family,
the sis gene family, and the myb gene family. At present, more than 100 kinds of
tumor suppressor genes have been discovered, and the most common ones are genes
such as Rb, P53, APC and nm23. Therefore, the activation of the different
proto-oncogenes and/or the inactivation of the tumor suppressor genes can lead
to the occurrence and metastasis of different types of malignant tumors.
The
strength of proto-oncogenes and the power of tumor suppressor genes maintain a
balance in good health. However, under the action of carcinogen, the power of
proto-oncogenes will become stronger, while the power of tumor suppressor genes
will become weaker. The physical, chemical, and biological factors that induce
cells to become cancerous are known as the carcinogens. Carcinogen is the "key"
to initiate the growth of cancer cells. The more "keys" there are, the greater
chance malignant tumors occur and metastasize.
Therefore, targeting the treatment of malignant tumors and metastatic cancer,
the multi-site, multiple gene-targeted medicines should be designed to inhibit
the proto-oncogenes, activate the tumor suppressor genes, and repair the damaged
apoptosis-regulating genes and DNA repair genes. In this regard, some studies
have demonstrated that natural herbal extracts have a very safe gene-targeted
therapeutic effect.
In
addition, we still have to eliminate various carcinogens as much as possible,
inhibit carcinogenicity in vivo, and actively develop anti-cancer ability in the
body. This includes conditioning of mental factors, nutritional and healthy
diets, and lifestyle changes, etc.
(II)
Androgen-dependent tumor
The
prostate is an androgen-sensitive organ, so its growth and functional
maintenance require proper androgen in the blood. Testosterone is the main
androgen in the blood circulation, which is converted to more physiologically
active (DHT) by the 5a-reductase in the prostate.
(DHT) is the main androgen for prostate growth. Under the
influence of some pathogenic factors, if the prostate is blocked, the
accumulation of DHT in the prostate can promote the enlargement of the prostate,
causing benign prostatic hyperplasia and prostate cancer.
At
present, there are a large number of clinical studies in the world that prove
(1) patients with prostate cancer are at low androgen levels; (2) when blood
testosterone (normally 15nmol/L) or free testosterone index (normally 4.0) is
lower than normal level, the incidence of prostate cancer may increase. Low
androgen levels in patients with prostate cancer often suggest a poor clinical
outcome.
Prostate
cancer patients are at low androgen level. The decrease of free testosterone
level may lead to the increase of 5a-reductase activity and increase the
conversion rate of testosterone to (DHT), thus increasing the risk
of metastatic prostate cancer.
Therefore, patients with prostate cancer may be at low testosterone levels and
high (DHT) levels. The main evidence in this regard is that (1)
patients with familial hereditary 5a-reductase deficiency never develop BPH and
prostate cancer; (2) Asian Americans with low risk of prostate cancer have
higher serum testosterone levels than European Americans with high risk of
prostate cancer; (3) Prostate cancer generally occurs in older people, and as
the age increases, the level of androgen in the body decreases, and the
incidence of prostate cancer will continue to rise.
Currently, for the clinical treatment of metastatic prostate cancer, the
traditional method is to use anti-androgen endocrine therapy, and the most
commonly used drugs are goserelin and bicalutamide which cause the blood
testosterone to a very low level very quickly with such common side effects as
sexual dysfunction, osteoporosis, liver function damage, anemia, depression and
so on. In the early stage, hormone-dependent prostate cancer (HDPC) can achieve
the goal of reducing tumors and decreasing blood PSA through endocrine therapy.
However, after 1 to 2 years of treatment, it gradually evolves into
hormone-independent prostate cancer (HIPC), which leads to the patient's death
from extensive metastasis of cancer cells.
Anti-androgen therapy makes patients’
androgen at a lower level, and causes anemia, nutrient deficiencies, mental
depression, decreased immunity, osteoporosis prone to fractures and many other
side effects, and ultimately leads to death from extensive metastasis of cancer
cells. Therefore, we oppose the use of longer-term anti-androgen endocrine
therapy.
On the
basis of maintaining normal levels of blood testosterone (normally 15 nmol/L),
we recommend that patients use a 5a-reductase inhibitor for longer periods of
time to reduce (DHT) levels in the prostate and metastatic
lesions, make the growth of cancer cells lack nutrients, which can achieve the
goal of inhibit and shrink tumors and reduce blood PSA. Long-term use of
chemically synthesized 5a-reductase inhibitors also has many side effects. We
recommend that patients use herbal extract 5a-reductase inhibitors of natural
origin without any side effects even after the long-time use.
(III) Tumor
microenvironment - "seeds and soil"
As early
as more than 100 years ago, the famous pathologist Stephen Paget proposed the
concept of "seed (cancer cells) and soil (internal environment)" for the
occurrence and metastasis of tumors. It has not received enough attention from
the medical community, and its treatment thinking has only confined to the tumor
cells themselves, causing humans' treatment roads towards tumors extremely
difficult. Until recently, oncologists began to realize that tumors and the
internal environment are an inseparable whole. The tumor microenvironment is the
internal environment in which tumor cells are produced and lived, including not
only the tumor cells themselves, but also various cells such as fibroblasts,
immune and inflammatory cells, glial cells, etc.. At the same time, it also
includes the interstitial cells, microvessels, and biomolecules infiltrated
therein in the nearby areas.
The
internal environment of the human body is mainly composed of micro-ecological
balance, nutrient metabolism balance and immune balance. For cancer patients,
these three balances are all unbalanced.
There are
many differences between the physical and chemical properties of the tumor
microenvironment and the normal internal environment of the human body. The most
obvious features are hypoxia, low PH, and high interstitial pressure. (1)
Hypoxic environment: There are hypoxic states in many malignant tumor tissues,
and necrosis often occurs in hypoxic regions, in which tumor spread and
metastasis are more likely to occur. (2) Low PH environment: The low PH of the
tumor microenvironment is on the one hand, in the case of hypoxia and a large
amount of glucose decomposition, glycolysis produces a large amount of lactic
acid and causes a decrease in PH. On the other hand, there are many kinds of ion
exchangers on the membrane system of tumor cells, which play an important role
in establishing the acidic environment of the tumor microenvironment. (3)
High-pressure environment: Due to the lack of functional lymphatic system in
tumor tissue, tumor vascular dysplasia leads to hypertonic vascularization,
which eventually leads to tumor interstitial high-pressure.
It is
precisely because of these characteristics that there are a large number of
immunoinflammatory reactions produced by growth factors, cell chemokines and
various proteolytic enzymes in the tumor microenvironment. This property is very
conducive to tumor proliferation, invasion and adhesion, angiogenesis, and
anti-radiotherapy and anti-chemotherapy, promote the occurrence of malignant
tumor metastasis. Such physical and chemical characteristics as hypoxia, low PH
and high pressure, they are not compatible with the normal environment, but
tumor cells can adapt well through various biological adjustments, and this
adaptation of tumor cells often leads to a vicious circle.
According
to the theory of tumor microenvironment, we design a new idea for treating
tumors:
The tumor
microenvironment is a complex system, and we need to understand the effects of
the entire microenvironment on the occurrence, development, and metastasis of
tumors. In terms of treatment design, we can first take natural herbal medicines
therapy to restore the internal environment balance of the human body, correct
the tumor microenvironment of hypoxia, low pH and high pressure, and cut off the
connection between the tumor microenvironment and tumor cells. In addition, we
should design multi-site and multi-target herbal treatment medicines, not only
to consider the tumor cells as "seeds", but also to consider the tumor
microenvironment as "soil", through which it is possible to obtain the better
therapeutic effects and lower the toxic side effects.
(IV)
Relationships between chronic inflammation and tumor
Inflammation is a defense response of the body to bad stimuli. Chronic
inflammation refers to the inflammation process lasting more than 3 months.
Any
factor that causes tissue damage can be the cause of inflammation, that is, the
inflammatory agent. Depending on the different inflammatory factors,
inflammation can be divided into infectious inflammation and non-infectious
inflammation. Infectious inflammation is caused by a variety of biological
pathogens, including bacteria, viruses, chlamydia, mycoplasma, fungi,
spirochetes, and parasites. While the non-infectious inflammation is mainly
caused by physical factors, chemical factors, and immune responses.
In recent
years, more and more research evidence indicates that tumor occurrence and
metastasis have a very close relationship with chronic inflammation. From a
certain perspective, cancer is also a chronic inflammatory disease. The
traditional immunology believes that immune cells help the body fight harmful
invaders and thus exert effective anti-tumor functions. However, in the actual
development of tumors, some immune cells often change from the "protector" of
the internal environment to the "accomplice" of tumor cells, promoting and
nourishing the development of tumors. When tumors become malignant, many
inflammatory immune cells are released into the tumor microenvironment for
participation and regulation, in which macrophages, neutrophils, mast cells and
so on play an important role. They release chemical chemotactic factors,
vascular growth factors and matrix degrading enzymes, which are beneficial to
tumor growth, invasion and metastasis. In addition, these immune cells continue
to produce peroxynitrite, a cell DNA damaging agent that is highly susceptible
to genetic mutations, activates cellular oncogene, and continuously produces new
cancer cells.
For the
relationship between infectious inflammation and cancer, it is just like that of
hepatitis virus and liver cancer, EB virus and nasopharyngeal cancer, HPV and
cervical cancer, Helicobacter pylori and gastric cancer, Streptococcus Bovis and
rectal cancer, and the like. For the relationship between non-infectious
inflammation and cancer, it is just like ulcerative colitis of immune diseases
leading to colon cancer, long-term smoking to respiratory inflammation and
tumor, long-term drinking to digestive tract inflammation and tumor, and so on.
There are also relationships between many undiscovered inflammations and cancer.
For example, the recent research suggests that Escherichia coli, Staphylococcus
epidermidis, and human cytomegalovirus (HCMV) are closely related to the
development and metastasis of breast cancer.
Even more
studies have shown that patients with extended-range cancer surgery, overdose of
chemotherapy and radiotherapy, will produce inflammation at the more parts of
the body, and are more likely to have metastatic cancer occurred at multiple
parts.
We have
also found in clinical treatment that all prostate cancer patients have had
inflammation in the prostatic fluid, and the degree of inflammation is
proportional to the extent of the tumor. And in patients who have undergone
prostate biopsy, the degree of inflammation in the prostatic fluid is also
significant.
In
addition, inflammation can also affect the treatment of tumors and the
prognosis, recurrence and metastasis of tumors. Therefore, for the cancer
treatment program, it needs to consider the inflammation and immune factors of
human body. If the relationship between various tumors and inflammation can be
clarified, anti-inflammatory drugs are often used which can completely prevent
and control the development and metastasis of tumors. However, long-term use of
chemically synthesized anti-inflammatory drugs such as adreno cortico hormones
and antibiotics can cause many side effects and is detrimental to tumor control.
Patients are recommended to use natural anti-inflammatory herbal extracts.
The Third
Part：How
does 3D Precision & Targeted Therapy Treat Metastatic Prostate Cancer
Survival
with tumor is the goal of long-term survival of patients with advanced cancer,
which is currently the main research direction of the medical community.
Survival with tumor is that the common cancerous symptoms get reduced or
disappeared, the local tumor volume is further shrunk without the cancer cells
spreading,cancer is in a stable state for a long time, the patient is generally
in good condition, and can work independently and life after the patient's
overall effective anti-tumor treatment. When the body's ability to inhibit
tumors continues to be greater than the ability of tumor growth and
proliferation, cancer cells are "quiet" and "dormant" for a long time, and the
patient is in a healthy state of long-term survival with tumors. Survival with
tumor can only be achieved by relying on the systemically effective anti-tumor
treatment in combination with the local treatment.
The goals
of 3D Precision & Targeted Treatment metastatic prostate cancer are to:
1) Reduce
and eliminate your symptoms, shrink the tumor.
2) You
may remain survival with tumor for a longer time than the average that was found
in various traditional treatments.
3)
Prostate cancer with distant metastasis has a 5-year survival rate of around 90%
from the current traditional treatment of around 29%.
3D
Precision & Targeted Therapy uses a systematic systems engineering to treat
metastatic prostate cancer. Patients can receive all or part of the medical
services under the guidance of the doctor based on their conditions.
We provide
the following medical services:
1) A
thorough treatment of intraprostatic tumors in a very safe and non-side effect
way
3D
prostate cancer precision & targeted local injection technique and anti-cancer
herbal medicines are used to kill all cancer cells in the prostate, thoroughly
treat intraprostatic tumors, make them no longer release cancer cells into the
spreading and metastatic channels.
At
present, for cancer patients with prostatic excretory ducts not destroyed, 3D
Prostate Precision & Targeted Treatment can significantly reduce or completely
eliminate tumors by killing cancer cells, decomposing tumors, and expelling
tumor material. However, for cancer patients with prostate excretory ducts have
been destroyed, the tumor continue to exist after treatment even after killing
cancer cells, decomposing tumor, because tumor substances unable to be
discharged. But the tumor will not continue to develop.
We
recommend that you make arrangements to come to our 3D Prostate Clinic in China
for a period of 4-6 weeks’
treatment.
2) An
oral natural anti-cancer herbal medicine is appropriate for the metastatic
cancer condition, and has no side effect nor adverse reactions. This natural
anti-cancer herbal medicine consists of various herbs extracts, which contains a
variety of bioactive components interacted specifically with cancer cells. The
studies have shown that they have anti-cancer effects on multiple sites and
multiple target points, such as inhibiting the activity of 5a-reductase and
proto-oncogenes, activating the activity of tumor suppressor genes, and
repairing the damaged Apoptosis regulatory genes and DNA repairing genes, etc.
so that you can treat your cancer at home.
We
recommend that patients can take this oral anti-cancer product of multi-site and
multi-target point for a long term, until the metastatic cancer has been well
controlled, and the patient is in a healthy survival condition with tumor.
3) An
oral natural anti-inflammatory herbal medicine that is appropriate for any
inflammatory condition, and has no side effect nor adverse reactions. This
natural anti-inflammatory herbal medicine consists of various herbs extracts,
which contains a variety of the interacted anti-inflammatory bioactive
components. The studies have shown that they have significant therapeutic
effects on various infectious inflammation and non-infectious inflammation, and
can alleviate or eliminate the symptoms of fever and pain caused by metastatic
cancer. In addition, this natural anti-inflammatory herbal medicine also has
such significant functions as anti-oxidation, discharging toxins from the body
and enhancing immunity, and it has a certain preventive effect on tumor
occurrence and metastasis.
We
recommend that patients take natural anti-inflammatory herbal medicine for 3-6
months.
4) An
oral natural herbal medicine for tumor microenvironment regulation, which has no
side effect nor adverse reactions. This natural regulatory tumor
microenvironment herbal medicine consists of various herbs extracts that
contains a variety of the interacted regulatory tumor microenvironment bioactive
components. The studies have shown that they can improve the internal
environment of cancer patients, correct cancerous constitution, make tumor
microenvironment of hypoxia, low PH and high pressure better, and have certain
auxiliary therapeutic effects on tumor occurrence and metastasis.
We
recommend that patients take this natural regulatory tumor microenvironment
herbal medicine for 3-6 months.
5) Other
treatments:
(1)
Treatment of chronic diseases: Instruct patients to actively treat chronic
diseases associated with cancer and metastatic cancer, such as chronic
infection, diabetes, hyperlipidemia, obesity, kidney disease, etc.
(2)
Treatment of tumors at the metastatic site: Different treatments are taken for
the characteristics of tumors at different metastatic sites. For example,
patients with bone metastases are advised to take oral botanical medicines for
preventing bone destruction and hematopoietic cells supplementation, because
cancer cells in the bone marrow will destroy sclerotin and hematopoietic cells
that can easily lead to fractures and anemia. These patients are not recommended
for endocrine hormone therapy as it is more likely to cause fractures and
anemia.
(3)
Treatment of metastatic cancer and complications: Metastatic cancer at different
sites and at different stages produces different symptoms and complications that
require symptomatic treatment. The most serious complications are anemia, edema,
and thrombosis. The situation will cause organism ischemia, hypoxia, acidosis,
and hypoproteinemia, which will worsen the microenvironment of the tumor and
cause extensive metastasis of cancer cells. Patients with severe complications
often have a poor prognosis with very low 5-year survival rate. The patients
with metastatic cancer are firstly to prevent the occurrence of these serious
complications, but if it occurs, they need to receive active professional
treatment.
(4)
Other palliative treatment: For example, targeting tumor compression nerves,
blood vessels, and other important lumens, the palliative surgery or
radiotherapy are used to reduce tumors and relieve pressure symptom. Others
include psychotherapy, natural therapy, etc.
Minimizing the Effects of Metastatic Prostate Cancer
As a
sufferer of metastatic prostate cancer, there are some significant things you
can do to minimize the effects of metastatic prostate cancer until you are a
member of our 3D clinic's family for successful treatment.
1)
Maintain some safe and reasonable treatments and medicines without side effects.
Avoid treatment that is unfavorable to metastatic cancer as much as possible,
including toxic medicines or drugs with great side effects, excessive surgery,
radiation therapy, and chemotherapy, etc.
2)
Maintain your psychological health: Psychological tension and excessive mental
stress are catalysts for the occurrence and metastasis of cancer cells in the
body. Stress and excessive excitement and depression can lead to the elevated
levels of adrenocortical hormones, which can reduce the body's immunity and are
vulnerable to various diseases including cancer. Cancer patients who receive
psychotherapy during their illness and are often encouraged by the positive
spirits of their relatives and friends generally obtain excellent treatment
results.
3)
Maintain aerobic exercise everyday: Exercise causes the human body to inhale
oxygen several times to several tens of times more than usual. Usually when
people is quiet, the oxygen intake is 4-7 liters per minute, while doing the
exercise, it can reach more than 100 liters. The increase in oxygen uptake and
the frequent exchange of gases can cause some carcinogens in the body to be
excreted; in addition, it can also better change the hypoxia microenvironment of
tumor in vivo.
In
addition, patients can also change the microenvironment of tumor growth in vivo
by drinking Ozone water generated by machine and inhaling negative Ion Air.
4)
Maintain a good sleep: At night, a melatonin is produced in the body, and the
property of its antioxidant protects the normal cellular DNA from the damage
caused by carcinogens in the body. It also inhibits the production of estrogen
which promotes the growth and development of certain tumors.
5)
Maintain a reasonable dietary structure: according to the World Health
Organization, 30% to 40% of male cancers and 60% of female cancers are related
to diet. People need to eat yellow and green vegetables, fruits, foods rich in
vitamins and carbohydrates. Pay attention to reduce high-salt foods. Eat less
pickled and marinated food. Avoid moldy foods. Pay attention to avoid high-fat
diet, and fat intake should be controlled below 30% of the total daily calories.
High-fat diets and obesity can cause endocrine hormone disorders, which are
associated with male prostate cancer and female breast cancer.
6)
Maintain a healthy lifestyle: Changing the bad habits and maintaining a healthy
lifestyle is the most economical and effective way to prevent the occurrence and
metastatic of cancer.
Experts
put forward 10 proposals for preventing cancer through reasonable living and
eating habits:
(1) Stop
smoking, do not drink alcohol, or restrict alcohol.
(2)
Avoid excessive sun exposure.
(3)
Encourage to do physical activity, adhere to physical exercise, and avoid
obesity.
(4) Open
mind, not sulking, keep a good mood.
(5) Hold
on to the grain, cereals, beans, sweet potatoes as the main staple foods, and
have crude and fine fiber foods properly matched.
(6)
Reduce meat intake and avoid animal fat.
(7) Eat
more fresh vegetables and fruits with vitamins A, C, and E that can reduce the
risk of many common cancers, especially dark leafy vegetables and carrots and
tomatoes.
(8) Food
storage should be mildewproof and do not eat moldy food.
(9) The
cooking method should be scientific, eat less salt and pickled food, do not eat
smoked, fired, fried, charred and over-hot food.
(10)
Protect the environmental health and reduce indoor and outdoor air pollution.
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